按照我女儿的说法，使他精神失常的是那地震。

According to my daughter it was the earthquakes that unhinged him.

youdao

简发现罗切斯特先生有个精神失常的妻子之后。

After Jane finds out Mr. Rochester has an insane wife.

youdao

也就是说，一种具有致幻剂作用原理但不会引起幻觉或精神失常的新药物。

In other words, a drug that treats depression the same basic way as a psychedelic but without any of the hallucinations and other mind-bending effects.

youdao

There are stories, horrible stories, some in the twentieth century, about children who are locked away by insane or evil parents and have never learned to speak.

有一些很可怕的故事,其中的一些讲述的是在二十世纪里,被精神失常或邪恶的父母锁起来的儿童,他们不曾学会说话

耶鲁公开课 - 心理学导论课程节选

And when my dad was here, he was in like, the sort of height of his crazy phase.

我父亲在这儿上学的时候，纳什的精神失常正处于最严重的阶段。

知道约翰·纳什吗？ - SpeakingMax英语口语达人