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结论天然雄黄可导致小鼠肝损伤，酸化精制后对肝脏毒性显著降低，雄黄毒性成分可能为可溶性砷盐。
CONCLUSION: Crude realgar could induce significant liver oxidative injury, which could be reduced by purified realgar. Soluble arsenic salt may be major toxic ingredient.
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