PYLL顺位与死因顺位不同，恶性肿瘤、损伤和中毒提升至前两位，循环系统疾病退至第三位。

The sequence of PYLL is different from death causes, with malignant neoplasm, accident and poisoning upgraded to the top two, circulatory system disease downgraded to the third.

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第三，由于肿瘤细胞来源的外泌体可修饰转移前微环境 境[6]，从循环系统中去除这些外泌体可能可以阻止癌症的转移。

Thirdly, considering cancer-cell derived exosome can modify pre-metastasis niches [6], depleting these exosomes from circulation system is a possible option for blocking cancer metastasis.

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