第三信使:负责细胞核内外信号转导的物质。
Its therapeutic mechanism have maybe a bearing on the expression of the c-fos protein considered as the third messenger in cortex and hippocampus. And this need further exploration.
结论:中药制剂抗痫胶囊能够有效对抗PTZ所致的惊厥发作,提高惊厥阈,延长潜伏期;其作用机理可能与下调皮层、海马内作为第三信使的c-fos蛋白的过度表达有关。
参考来源 - 抗痫胶囊的抗惊厥效应及其对戊四唑惊厥小鼠皮层、海马c·2,447,543篇论文数据,部分数据来源于NoteExpress
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