Alzheimer病典型的显微镜表现包括“老年斑”与星形胶质细胞和小胶质细胞，老年斑是变性的突触前末梢。

The characteristic microscopic findings of Alzheimer's disease include "senile plaques" which are collections of degenerative presynaptic endings along with astrocytes and microglia.

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免疫电镜还显示有TH阳性神经元胞体和轴突末梢，后者可作为突触前成分与TH阴性结构形成突触。

Especially, there were TH-like positive cell bodies and axonal endings which formed synapses as presynaptic elements with th negative postsynaptic structures.

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another thing that you'd find if you looked inside the axon terminals of any of these pre-synaptic membranes, you'd find lots of vesicles or some membrane bound compartments that contain special chemicals called neurotransmitters.

如果你仔细观察,突触前膜的轴突末梢内部,你会发现很多小泡,即膜包被的结构,包含有称为神经递质的特殊化合物

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If you could look inside a pre-synaptic axon terminal, you would find one of the characteristics is that it's loaded with these vesicles and they're just sitting there waiting to receive an action potential so that they can immediately dump their contents.

如果你能够一窥突触前的轴突末梢内部,你将会发现一个共同特征,神经递质都装载在小泡中,时刻准备着等待动作电位激活,以便迅速释放其内含物

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