EAE可以用同种或异种中枢神经系统白质抗原主动诱导敏感动物发病,与MS有很多共同的特点。
EAE can be induced actived by syngeneic or heterogeneous antigen from white matter of CNS. It shares many feathers with MS.
实验性自身免疫性脑脊髓炎(eae)是一种免疫细胞介导的以中枢神经系统白质损坏为特征的自身免疫性疾病。
Experimental allergic encephalomyelitis (EAE) is an immune disease, whose character is the damage of white matter of nervous system mediated by immunocyte.
虽然当PrP缺失时,施沃恩细胞会受到疾病侵袭,蛋白质还是应该存在于轴突以防止疾病发生。这项研究成果发表在本周的《自然——神经系统科学》。
Even though the Schwann cells are the ones affected when PrP is missing, the protein must be present in axons to prevent disease, the researchers report online this week in Nature Neuroscience.
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