Racemic backbones 2-amino-2’-hydroxy-6,6’-dimethyl-l,l’-biphenyl la and 2-amino-2’-hydroxy-4,4’,6,6’-tetramethyl-l,1’-biphenyl 1b were synthesized from o-methylaniline and 2,4-dimethylaniline via nitration, diazotation/iodination, Ullmann coupling, selective reduction, diazotation/hydrolysis and hydrogenation.
从邻甲苯胺及2，4-二甲基苯胺出发，经过硝化，重氮化-碘代，偶联，单还原，重氮化-水解及还原反应合成了消旋体骨架2-氨基-2’-羟基-6,6’-二甲基-1，1’-联苯1a和2-氨基-2’-羟基-4，4’，6，6’-四甲基-1，1’-联苯1b。
参考来源 - 手性联苯骨架的合成及其在不对称催化中的应用·2,447,543篇论文数据，部分数据来源于NoteExpress
报道了二碘代苯酐的合成研究。
The paper focused on the study of synthesis of diiodophthalic anhydride.
本文用均匀设计法优化了碘代酚的合成工艺。
The synthetic procedure of the title compound was optimized by using uniform design.
结果表明，在此催化剂作用下，碘代苯与丙烯酸反应具有较好的立体选择性，只生成反式苯丙烯酸；
The result shows that, under this catalytic reaction, the Heck arylation of iodobenzene with acrylic acid has a good stereoselectivity and only trans-cinnamic acid is produced.
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