盐酸恩丹西酮胶囊，是一强效、高选择性的5-HT3受体拮抗剂,有强止吐作用剂。化疗药物和放射治疗可造成小肠释放5-HT，经由5-HT3受体激活迷走神经的传入支，触发呕吐反射。本品能阻断这一反射的触发。迷走神经传人支的激动也可引起位于第四脑室底部Postrema区的5-HT释放，从而经过中枢机制而加强。
品名称】通用名称：盐酸恩丹西酮胶囊英文名称：Ondansetron Hydrochloride Capsules拼音名称： 【成份】盐酸恩丹西酮 【性状】胶囊，内容物为白色颗粒。 【适应症】止吐药。用于：①细胞毒性药物化疗和放射治疗引起的恶心呕吐；②预防和治疗手术后的恶性
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文章摘要：目的：制定盐酸恩丹西酮缓释胶囊的质量标准。
Abstract: Objective: To develop the quality standard of ondansetron hydrochloride sustained release capsules.
目的：制备盐酸恩丹西酮缓释胶囊并建立其质量控制方法。
METHODS: Ondansetron hydrochloride sustained release capsule was prepared and its release rate was determined, and its releasing mechanism and the influence factors were studied.
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