皮恩扎(Pienza)是意大利中部托斯卡纳大区锡耶纳省的一个市镇,毗邻蒙塔尔奇诺,被称为“文艺复兴都市生活的试金石”。
萨皮恩扎说,下一步是要反复研究更多的基因。
Sapienza says the next step is to repeat the study looking at more genes.
是生殖技术抑或不育的副作用造成甲基化缺陷仍是未知之数,但萨皮恩扎计划在未来的研究中整理出答案。
Whether it's the reproductive technology or some by-product of infertility causing the methylation defects is still unknown, but Sapienza plans to tease out the answer in future studies.
但这种机制尚不完善:“如果你审视肿瘤,它们往往具备整体低甲基化,但某些基因却超甲基化,”萨皮恩扎说。
But the mechanism isn't perfect: "If you look at tumors, they tend to have hypomethylation overall, but hypermethylation in some genes," Sapienza says.
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