目的：用SELDI蛋白质芯片技术检测HBV感染携带者与肝细胞癌（HCC）患者血清蛋白质谱的差异性表达，以发现HCC的早期诊断标志物。

Object Using SELDI protein chip technology to detect the different serum protein spectrum of HBV infected carriers and HCC patient , and to explore serum markers for diagnosis of HCC.

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结论CA125不只是卵巢癌的指标，也是一种广谱肿瘤标志物，并且肝硬化等良性疾病也有较高的阳性率，可作为健康体检中筛选异常人群的指标。

Conclusion: CA125 is not only a marker for ovarian cancer, but a broad-spectrum tumor marker. There are higher positive rates of CA125 in some benign diseases including hepatocirrhosis.

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目的比较不同转移潜能人肝癌细胞系的基因表达谱，寻找与癌转移相关的基因表达改变。

Objective to compare gene expression profile of human hepatocellular carcinoma (HCC) cell lines with different metastatic potentials, so as to screen for metastasis-related genes.

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