目的：用高效液相色谱法（HPLC）测定消痤宁乳膏主要有效成分克林霉素和甲硝唑的含量并拟定该乳膏剂的质量标准草案；进行消痤宁乳膏的药效学研究和观察其毒性。

Objective:To determine the main contents metronidazole and clindamycin of the Xiaocuoning cream by HPLC and establish quality control method, study the pharmacodynamics and observe its toxicity.

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