甲营养不良是一种多因素引起的甲损害。常累及所有指,趾甲。患者指(趾)甲变薄,浑浊,变形,易碎。甲表面失去光泽,粗糙。常有纵嵴及甲剥离。真菌镜检阴性。无有效治疗方法。部分患者病情随年龄增长逐渐缓解。
先证者双肘膝关节毛囊角化性丘疹,足趾及跖部灶性胼胝样角化过度,20甲营养不良。
Proband also had special clinical feature including follicular hyperkeratosis on the elbows and knees, and onychodystrophy of 20 nails as well.
一种遗传疾病,以先天性局部皮肤缺损、大疱性表皮松解症、口腔粘膜病变、甲营养不良为特征。
Bart syndrome is a genetic disorder characterized by the association of congenital localized absence of skin, epidermolysis bullosa, lesions of the mouth mucosa, and dystrophic nails.
药物动力学数据表明,正常剂量的青霉素、复方磺胺甲恶唑和庆大霉素对于营养不良的儿童是安全的,而氯霉素的剂量或服用频率需要调整。
Pharmacokinetic data suggest that normal doses of penicillins, cotrimoxazole and gentamicin are safe in malnourished children, while the dose or frequency of chloramphenicol requires adjustment.
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