H2受体拮抗剂，能明显地抑制食物、组胺或五肽胃泌素等刺激引起的胃酸分泌，并使其酸度降低。本品对因化学刺激引起的腐蚀性胃炎有预防和保护作用，对应激性溃疡和上消化道出血也有明显疗效。
甲氰咪胍治疗上消化道出血的效果与引起出血的病因有关。
Cimetidine was effective in the management of the upper GI bleeding from peptic ulcer.
方法：分三组分别接受米索前列醇、甲氰咪胍和不接受预防性药物。
Methods: Three groups were treated with intragastric misoprostol, cimetidine, and placebo respectively.
目的：探讨甲氰咪胍对肝硬化门脉高压症犬门脉血液动力学的影响。
Objective To investigate the effects of Cimetidine on portal hemodynamics in dogs with cirrhosis and portal hypertension.
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