The mechanism maybe inhibit the infiltration and activation of macrophages,and reduce the expression of IL-1βin activated macrophages by inhibit the the phosphorylation of p38 kinase.
其作用机制可能是通过抑制巨噬细胞p38激酶磷酸化,抑制巨噬细胞浸润和活化,并减少活化巨噬细胞IL-1β的表达水平,从而达到治疗MsPGN的作用。
参考来源 - 五肽化合物PLNPK对抗Thy1系膜增生性肾小球肾炎的治疗作用及机制探讨·2,447,543篇论文数据,部分数据来源于NoteExpress
目的:探讨脊髓损伤后活化巨噬细胞移植的时机和脊髓功能恢复之间的关系。
Objective: To investigate the correlation between the opportunity of activated macrophages transplantation and the restoration after the spinal cord functions of the spinal cord injury (SCI).
很多细胞活动会使T细胞应激产生淋巴因子,如中性粒细胞、巨噬细胞和淋巴细胞的吸附和活化。
Stimulated t cells produce lymphokines with a wide range of activities, such as attraction and activation of neutrophils, macrophages, and lymphocytes.
目的探讨肺泡巨噬细胞活化在急性坏死性胰腺炎(ANP)肺损伤中的作用。
Objective To discuss the role of alveolar macrophage activation in rats with acute necrotizing pancreatitis (ANP) associated with lung injury.
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