Part 1 IntroductionIn this part, we briefly introduced the commercial nitrogen mustard agents, and the related anti-tumor mechanism. Recent study and prospect of nitrogen mustard derivatives were also summarized.
1前言介绍了常用的氮芥类药物及作用机理,以及氮芥衍生物的研究现状及前景,同时简要介绍了本课题的研究内容。
参考来源 - 芳香氮芥衍生物的合成及生理活性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
首次设计并制备了二种以茄呢基胺和茄呢基哌嗪为载体的新型氮芥衍生物。
Two new nitrogen mustard compounds using solanesylamines as the targeted carriers were first designed and synthesized.
以2-苯基-4-喹啉酮为原料，通过磷酰化反应将磷酰氮芥引入到2-苯基-4-喹啉酮中，合成了一种新型的喹啉-4-氨基磷酸酯衍生物。
In this study, phosphoramide mustard was coupled to 2-phenyl-4-quinolone by a facile phosphorylation reaction to yield a novel quinoline-4-phosphoramidate derivative.
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