目的研究在体外5-氮胞苷诱导骨髓间质干细胞定向心肌向分化的条件。
Objective To investigate the effect of 5-azacytidine on cardiomyogenic differentiation of bone marrow mesenchymal stem cells (BMSCs).
结果大鼠骨髓基质细胞贴壁呈集落生长,5 -氮胞苷诱导骨髓基质细胞转化为心肌样细胞。
Results Mesenchymal stem cells were spindle-shaped and active proliferation capacity in vitro, they can be differentiation into cardiac-like muscle cells after adding 5-azacytidine.
氮杂胞苷(Azacitidine),用于治疗骨髓增生异常综合征(MDS) 一种罕见的恶性血液肿瘤。
Azacitidine is used to treat patients with myelodysplastic syndromes (usually abbreviated, a bit oddly, to MDS), a group of rare and deadly blood malignancies.
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