氨力农(3-amino-5-pyridin-4-yl-1H-pyridin-2-one)化学名为5-氨基-[3,4'-双吡啶]-6(1H)-酮,淡黄色至淡黄棕色针状结晶或结晶性粉末;无臭,无味;遇光色渐变深。本品在甲醇中微溶,在乙醇中极微溶,在水中几乎不溶;在乳酸中溶解。分子式为C10H9N3O,分子量为187.19800,密度为1.277 g/cm3,熔点为294-297ºC,沸点为451.5ºC at 760 mmHg。
氨力农(Amrinone)是近年来人工合成的非洋地黄类非儿茶酚胺类、具有正性肌力和扩张血管作用的抗心力衰竭新药[1].1996年8月-1999年8月,我们应用氨力...
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对36例充血性心衰患者进行了国产静脉用氨力农效应血流动力学观察。
The hemodynamic effects of domestic amrinone on 36 patients with congestive heart failure were observed.
目的:研究氨力农对慢性肺心病急性发作期患者的心功能、肺动脉压PAP的作用。
Objective:To study the effect of amrinone on the cardiac function and pulmonary arterial pressure (PAP) in patients with acute exacerbation of chronic pulmonary heart disease.
结果显示氨力农能显著增加CI,降低PCWP,轻度降低血压,对心率无明显影响。
Results showed that CI was significantly increased, PCWP was decreased, blood pressure was slightly decreased by amrinone but no significant effect on heart rate.
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