又称毒性效应。早年称毒性作用或毒作用。指毒物或药物对机体所致有害的生物学变化,如痉挛、致畸、致癌或致死等效应。例如氟乙酰胺经体内脱胺,生成氟乙酸,再经活化后在缩合酶的作用下,与草酰乙酰缩合,生成与柠檬酸结构相似的氟柠檬酸,抑制乌头酸、干扰机体正常三羧酸循环而产生神经系统和心脏毒效应。
化学物对机体产生的有害作用称为毒效应(toxic effect),也常称为毒性作用或毒作用。毒效应和毒性的概念是有区别的,毒性是化学物固有的生物学内在属性,我们不能改变化学物的毒性,而...
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中毒效应 poisoning effect ; poisonous effect ; effect poisonous
铍毒效应 berylliosis
毒效应谱 spectrum of toxic effects
急性毒效应区 acute toxic effect zone
慢性毒效应区 chronic toxic effect zone
毒物兴奋效应 [毒物] Hormesis
细胞毒效应 antibody dependent cell mediated cytotoxicity ; ADCC
的细胞毒效应 antibody dependent cell mediated cytotoxicity ; ADCC
酮类的毒性效应 Toxic effect of ketones
Sodium salicylate is an anti-inflammatory drug widely used in the clinical,however,studies in recent years suggested that high doses of the therapeutic effect of sodium salicylate may have potential therapeutic effects on PQ-induced toxic effects.
水杨酸钠是临床上常用的抗炎药,近年来的研究提示高剂量的水杨酸钠对PQ所致的毒效应可能具有潜在的治疗效果。
参考来源 - 水杨酸钠对百草枯所致大鼠肺损伤的干预研究·2,447,543篇论文数据,部分数据来源于NoteExpress
本文就环境雌激素毒效应的作用机制及检测方法进行综述与展望。
The toxicity active mechanism and methods of test have been introduced, and the prospects of studies have been forecasted in the article.
研究背景:在多发性硬化的病变过程中通过多种细胞毒效应产生过氧化氮阴离子。
Background: Peroxynitrite was hypothesized to be involved in the pathogenesis of multiple sclerosis through its various neurotoxic effects.
自噬的抑制能够增强5 - FU对结肠癌CD 133 +细胞的细胞毒效应。
Inhibition of autophagy may be employed to increase the cytotoxic effect of CD133 + CSCs to 5-fu.
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