目的探讨副肿瘤性天疱疮（PNP）患者血清中抗桥粒芯蛋白（DSG）抗体与头皮脱发之间的关系。
Objective To investigate the relationship between the levels of antidesmoglein(DSG)1, 3 antibodies in the sera of patients with paraneoplastic pemphigus(PNP)and alopecia.
结论： 桥粒芯糖蛋白1+2在皮肤鲍温病中表达部分下调，可能与肿瘤的恶性程度有关。
Conclusion: The expression of desmoglein 1+2 is partly down regulated in Bowen disease, and may be related to the high and low malignancy of tumor.
目的：扩增人表皮角质形成细胞桥粒芯糖蛋白4胞外区域EC 1, EC 2, EC3和EC4的核酸序列。
AIM To amplify the nucleotide sequence of desmoglein 4 extracellular domains EC1 EC2, EC3 and EC4 from human keratinocytes.
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