核苷酸(hé gān suān) Nucleotide,一类由嘌呤碱或嘧啶碱、核糖或脱氧核糖以及磷酸三种物质组成的化合物。又称核甙酸。戊糖与有机碱合成核苷,核苷与磷酸合成核苷酸,4种核苷酸组成核酸。核苷酸主要参与构成核酸,许多单核苷酸也具有多种重要的生物学功能,如与能量代谢有关的三磷酸腺苷(ATP)、脱氢辅酶等。
n. nucleotide
核苷酸(Nucleotide)是由含氮的碱基、核糖或脱氧核糖、磷酸三种分子连接而成。碱基与糖通过糖苷键连成核苷,核苷与磷酸以酯键连成核苷酸。
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...rleukin-12,IL-12)基因修饰瘤苗联合含非甲基化的胞嘧啶鸟嘌呤二核苷酸(CpG)基序的寡脱氧核苷酸(oligodeoxynucletide,ODN)即CpG-ODN治疗小鼠眼内黑色素瘤的疗效。
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...剂型而对其它给药途径效果不佳;在注射部位会产生红肿刺激和皮下结节等副作用。含有去甲基化的CpG结构模式的寡聚核苷酸(CpG-ODN)是Toll样受体9的激动剂,作为免疫佐剂已有部分亚型进入了I期临床阶段,然而其应用可能造成免疫系统稳态的破坏,甚至诱发自身免疫...
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寡核苷酸 [生化] oligonucleotide ; ODN ; oligo ; TFO
核苷酸基转移酶 nucleotidyltransferase
烟酰胺腺嘌呤二核苷酸 nicotinamide adenine dinucleotide ; NAD ; NADH ; coenzyme
核苷酸切除修复 nucleotide excision repair ; NER ; excision repair
双脱氧核苷酸 Dideoxynucleotide ; ddNTP ; dideoxy nucleotide
嘌呤核苷酸循环 [生化] purine nucleotide cycle
核苷酸交换因子 Nucleotide exchange factor ; guanine nucleotide exchange factors ; GEFS
单核苷酸多态性 SNP ; Single Nuclear Tide Polymorphisms ; single nucleotide polymo ; Haplotype-tagging SNPs
脱氧核苷酸 [生化] deoxynucleotide ; deoxyribonucleotide ; deoxyribonucleoside monophosphate ; deoxyribotide
It has 15 nucleotides deletion in NS.
NS基因有15个核苷酸缺失。
参考来源 - 高致病性禽流感病毒A/Duck/Guangxi/53/02株感染性克隆构建及分子演化研究Nucleotide diversity (n)was lower, only 0.0204.
核苷酸多样度(π)比较低,仅有0.0204。
参考来源 - 东北区狍遗传多样性及性别基因鉴定研究This kind of intramolecular and intermolecular hydrogen bonding plays a pivotal role in molecular conformation, crystal packing, protein folding and the binding between some nucleoside bases.
这类分子间氢键和分子内氢键在分子构型、晶体堆积、蛋白质折叠和核苷酸间的成键中都起着非常重要的作用。
参考来源 - 组氨酸衍生物荷质转移的理论研究·2,447,543篇论文数据,部分数据来源于NoteExpress
那可能发生的,但属于非正常的变化,但是可能主链的化学变化将核苷酸结合在一起。
That can happen but that's abnormal, but changes in maybe the chemistry of the backbone that holds the nucleotides together.
然后,含有这些信使核糖核苷酸的脑细胞就可以被分离开来,研究者可对其信使核糖核苷酸进行解码,以确定它们的蛋白质产物究竟是什么,并确定这些蛋白质产物在何种程度上类似于真正的肽激素。
The brain cells containing these mRNA's can then be isolated and their mRNA's decoded to determine just what their protein products are and how closely the products resemble the true peptide hormones.
二脱氧核苷酸是 DNA 聚合酶的链延长抑制剂。
Dideoxynucleotide is chain-elongating inhibitor of DNA polymerase.
That can happen but that's abnormal, but changes in maybe the chemistry of the backbone that holds the nucleotides together.
这可能发生的,但属于非正常的变化,而是改变诸如维持核苷酸序列的,主链的化学结构
It's easy to know what nucleotide to put in each position as you're going along and polymerizing a new molecule.
这使得复制过程中决定下一个核苷酸位点,应该用哪一个核苷酸更为容易
What's hanging off of the side of this long molecule that's formed by polymerizing nucleotides are - is this base unit.
在这条由多聚核苷酸,构成的长链分子,一侧悬挂着碱基单位
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