核剪接(nuclear splicing) 核剪接是指发生在细胞核中,主要是对hnRNA中内含子的剪接。 这种剪接有三个主要特点∶ 第一是在pre-mRNA中内含子与外显子间有特征性序列,即GT-AG规则; 第二是剪接过程中需要snRNA参与,并要形成剪接体; 第三要形成套索结构。
RNA剪接是由一个上百个蛋白质和数条小核r NA组成的复杂的动态复合体完成的。
RNA splicing is carried out by the spliceosome, which is a large, dynamic complex composed of more than a hundred proteins and several small nuclear RNAs.
为对真核基因的选择性剪接形式进行准确、快速、有效的研究,提出了一种启发式多序列比对算法。
A heuristic algorithm for multiple alignment was developed to more effectively study alternative splicing patterns of eukaryotic genes.
精确预测剪接位点是真核基因系统研究的第一步。
Accurate prediction for splice sites is the primary step in the system research for eukaryotic genes.
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