柚皮素(naringenin)在7 碳位处与新橙皮糖成苷，称柚皮苷，味极苦。其在碱性条件下开环、加氢形成二氢查耳酮类化合物时，则是一种甜味剂，甜度可达蔗糖的2 000 倍。橙皮素大量存在于柑橘皮中，在7 碳位处与芸香糖成苷称橙皮苷，在7碳位处与β-新橙皮糖成苷，称为新橙皮苷。
n. naringenin
Index of ACA: Fructus Aurantii Immaturus: Naringin- Hesperidin- Poncirin- Neohesperidin- Naringenin- Hesperetin(223.66:18.50:254.49:321.00:4.46 : 1 ) ;Fructus Ponciri: Naringin-Hesperidin-Poncirin- Naringenin- Hesperetin(514.55:16.37:2454.23:20:1).4.
药效组分指标:枳实的药效组分为柚皮苷-橙皮苷-枸橘苷-新橙皮苷-柚皮素-橙皮素（223.66:18.50:254.49:321.00:4.46:1）。
参考来源 - 枳实降血脂药效组分生物效应评价方法研究·2,447,543篇论文数据，部分数据来源于NoteExpress
采用直接用水加热提取柚皮苷，再酸水解得到柚皮素。经核磁共振鉴定所得苷元为高纯度的柚皮素。
The naringin was extracted from Citrus grandis' Tomentosa' by water and hydrolyzed with acid to get naringenin. The structure of naringenin was determined by NMR and chemical reaction.
英国糖尿病协会去年报告的以前的研究，也宣布过，柚皮素能预防体重增加，平衡葡萄糖和胰岛素水平。
Previous research, which Diabetes UK reported on last year, also claimed that naringenin could prevent weight gain and balance glucose and insulin levels.
研究者还发现，柚皮素能拮抗药物摄取的关键转运体，OATP1A2，它能使药物从小肠转运到血液中。
The team also found that naringin appeared to block a key drug uptake transporter, OATP1A2, which has a role in transporting drugs from the small intestine into the bloodstream.
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