染色质由卷曲的DNA、组蛋白和非组蛋白组成。
Chromatin consists of coiled DNA bound to basic proteins called histones and non-histone proteins.
操作上讲，修饰功能或者通过中断染色质接触或通过影响非组蛋白蛋白质招募到染色质上。
Operationally, modifications function either by disrupting chromatin contacts or by affecting the recruitment of nonhistone proteins to chromatin.
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