研究人员说，多出来的拷贝改变了染色体的结构，它使得这个区域失去了活性因此无法使用。
Researchers say that those extra copies change the chromosome's structure, shutting off the whole region so it cannot be used.
染色体结构改变造成遗传物质的重新排列。若为非平衡型重排，则可导致异常表型。
Rearrangement — Chromosome breakage followed by reconstitution in an abnormal combination. If unbalanced, the rearrangement can produce an abnormal phenotype.
它涉及到染色体结构的改变、顺式作用元件和反式作用因子相互作用等多种过程。
Many events such as the alteration of chromatin structure, the interaction between cis-elements and trans-factors are involved in this process.
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