目的：探讨注射用二磷酸果糖致急性高磷血症的临床特点及诱发急性肾功能衰竭的发病机理。

Objective: to investigate the clinical characteristics and mechanism of renal failure due to acute hyperphosphatemia following intravenous fructose diphosphate injection.

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高果糖饲料喂养4周后，大鼠出现高血糖、高胰岛素血症、胰岛素抵抗、高血压和高脂血症。

Howevever, after feeding with high fructose diet for 4 weeks, hyperglycemia, hyperinsulinemia, insulin resistance, hypertension and hyperlipidemia occurred in the SD rats.

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