那是困扰我们现代生活方式的最棘手的其中一个问题。
It's one of the most difficult problems besetting our modern way of life.
在一些最棘手的问题上，他的待办事项清单令人沮丧地不足。
His to-do list was dispiritingly inadequate on some of the thorniest problems.
怎样处理金融票据是目前最棘手的问题。
How to treat financial instruments is by far the toughest question.
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