然而，抗逆转录病毒疗法常常晚期才会被采用，无论是在使用抗逆转录病毒疗法之前和之后，项目内的儿童过早出现死亡和损失都是主要的问题。

However, ART was often given too late, and early mortality and losses to programme before and just after ART initiation were major problems.

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Pfizer的crizotinib专门攻击某种基因转录的蛋白，只有少于5%的非小细胞肺癌患者具有这种基因。 Roche的vemurafenib通过阻断基因B-RAF的变异体抵抗晚期黑色素瘤。

Pfizer's crizotinib attacks a protein encoded by a gene found in fewer than 5% of patients with non-small-cell lung cancer.

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