结论手术治疗对痛风晚期进行痛风石清除有效，同时也可纠正畸形及外形，改善手功能。
Conclusion Operative treatment can effectively remove tophus in late gout, and correct deformity and improve function of the hand.
早期有游走性关节疼痛、肿胀和功能障碍，晚期则表现为关节僵直和畸形，功能丧失，导致残疾。
In the earlier period, it show mobile arthrosis ache, swelling and dysfunction; while in the advanced stage, it show arthrosis rigor, deformed, functional incapacitation or even disability.
方法对妊娠中、晚期孕妇进行超声检查，发现畸形胎儿与分娩后作对比。
Methods The pregnant women performed ultrasound examinations during second or third trimester in our hopital, if abnormal fetus were found and compared after childbirth.
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