...上问题,国内外近年来常用集数学和统计学方法于一体的星点设计效应面优化法进行试验设计,星点设计(central composite design,CCD)是一种新型的试验设计方法,它具有试验次数少,试验精度高等特点,在 药学应用上成效显着。
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...星点设计-效应面法;高效液相色谱法;药动学 [gap=2073]Key words: aripiprazole; sustained-release microsphere; central composite design-response surface methodology; HPLC; pharmacokinetics ..
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星点设计-效应面法 Central Composite Design/Response Surface Method
结论:星点设计法使用方便、预测性良好,值得推广应用。
CONCLUSION: Central composite design is convenient to use and it has satisfactory predictability thus deserving popularization.
目的:采用星点设计-效应面法优选消疮凝胶剂的提取工艺。
Objective: To optimize the extraction craft of Xiaochuang gel by central composite design-response surface methodology.
目的通过星点设计-效应面法优化替硝唑结肠靶向生物黏附片处方。
OBJECTIVE To optimize the formulation of tinidazole colon-targeted bioadhesive tablets by the central composite design-response surface methodology (RSM plus CCD).
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