我们对此项工作是基于1979年Sheiner[10]把经典的药物动力学模型加以扩展,提出一个假设的效应室(effect compartment)来与血浆室相联系,将传统的药代动力学和药效动力学结合起来,构成药代动力和药效动力学结合模型,简写PK/PD模型即通常称为PK/PD结合...
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效应室靶浓度 target effect-site concentration
温室效应 [地物] Greenhouse Effect ; greenhouse ; Global warming ; hot house effect
效应室消除速率常数 Ke
效应室浓度 effect compartment concentration
时效应室浓度 effect compartment concentration
温室效应潜能值 GWP
温室效应气体 GHG ; GreenhouseEffectGas
致温室效应气体 greenhouse-effect gas ; greenhouse gas ; GHG ; effect gas
温室效应潜值 GWP
结论靶控效应室浓度输注异丙酚时,效应室浓度与BIS的变化不完全一致可能是药代动力学参数造成的差异。
Conclusion The inconsistency of BIS with effect-site concentration during TCI of propofol may result from its pharmacokinetic parameters.
尽管这些感觉是暂时的,但是这种效应可能对进行精细程序的工作人员有安全影响(例如外科医生在核磁共振室进行操作)。
Although only temporary, such effects may have a safety impact for workers executing delicate procedures (such as surgeons performing operations within MRI units).
据预测,这一效应非常小,以至于超越了实践经验和地面的实验室测量手段。
This effect is expected to be so small that it is beyond practical experience and ground laboratory measurement.
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