目的探讨受照后淋巴细胞DNA双链断裂和凋亡作为放射损伤生物学检测指标的可行性。
Objective to investigate the possibility of applying the DNA double strand break and apoptosis of lymphocytes to biological assay in radiation injury.
来自AT病人的细胞显示有缺陷的DNA损伤诱导检验点激活,对放射的敏感性和频率较高的染色体断裂(3,4)。
Cells from at patients display defective DNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage (3, 4).
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