...心 关键词】 拳参正丁醇提取物 左心房 兴奋性 功能性不应期 [gap=742]Key words:Polygonum Bistorla's n-Butyl alcohol extract; Pulmonary atrium; Excitability; Functional refractory period ..
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拳参通过95%的乙醇提取后,再依次用石油醚、醋酸乙酯、正丁醇萃取,其正丁醇萃取部分即得拳参正丁醇提取物(PBNA),主要成分为丁香苷、芦丁、儿茶素及Mururin A[1]。
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即得拳参正丁醇提取物 PBNA
目的研究拳参正丁醇提取物对豚鼠离体右心房自律性及收缩特性的影响,并探讨其作用机制。
ObjectiveTo investigate the effect of Polygonum Bistorla L. n-Butyl alcohol extract on autorhythmicity and contraction of isolated right atrium of guinea pig and its mechanism.
结论拳参正丁醇提取物对异丙肾上腺素所致大鼠心肌肥厚具有保护作用,其作用机制与清除OFR和提高NO水平有关。
ConclusionBAEB has a protective effect on myocardial hypertrophy caused by Iso, and its mechanism may be related with clearance of OFR and NO concentration promotion.
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