细胞在成熟过程中通过T细胞表面受体基因重排，从而具有特异性识别抗原的能力，在这一过程中的任何失调都会导致疾病。
T cell receptor (TCR)gene rearrangement is an important event in T cell ontogeny that enables T cells to specifically recognise antigens, and any dysregulation in this process may result in diseases.
目的体外建立可长期培养的抗原特异性T细胞系及克隆，并分析其T细胞受体的使用情况。
Objective To establish long-term cultured antigen-specific T cell line and clones and to analyze their T cell receptor usage.
目的探索建立受体针对供体抗原特异性T淋巴细胞克隆，转入自杀基因诱导移植耐受的可行性。
Objective to explore the feasibility that the recipient against donor antigen specific t lymphocytes clones are formed, and the suicide genes are induced into the clone.
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