由于该机制可影响特定抑癌基因的活性，因而与肿瘤形成密切相关。
This mechanism is particularly relevant in cancer since it can interfere with the activity of specific "suppressor" genes.
结果山豆根总生物碱有一定的抗肿瘤活性，但抑瘤率低，毒性大。
RESULT the total alkaloids of Radix Sophorae Tonkinensis had anti - tumor effect, but the tumor - inhibiting rate was low with great toxicity.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
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