这种研究方法能够提供一定的基因表达水平的相关信息,如在筛选肿瘤标记(tumor marker)或药物靶点(drug target)时就非常有用,但却不能提供细胞在某一生物过程中mRNA表达的全景式的信息。
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那是旨在使其更活跃的药物或其他措施的理想靶点。
"That makes it an ideal target" for drugs or other measures designed to make it more active.
已有部分靶向药物进入临床或进入临床试验,本文分别对其靶点和作用机制进行概述。
Part of the targeted drug have been entered clinic or clinical trials. Their target and mechanism of action are summarized as follow.
文章从细胞信号传导通路、细胞生存途径、基因治疗及血管生成四方面简要介绍这些新靶点和已经或正在研发的新药物。
This review briefly focused on the new targets and agents from the following four aspects: signal transduction pathway, cell survival pathway, gene therapy, and angiogenesis.
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