西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料，经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯；
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
以聚丙烯腈纤维为原料，加入羟胺试剂，将腈基转变为偕胺肟基团，使聚丙烯腈纤维改性成含有偕胺肟基团的螫合纤维。
Polyacrylonitrile fiber was modified into a chelating fiber containing amidoxime group by adding hydroxylamine, resulting from that nitrile group was transformed into amidoxime group.
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