目的:探讨肾上腺髓质素(AM)在慢性低氧性肺动脉高压发病中的作用。
AIM: To study the role of adrenomedullin (AM) in the pathogenesis of hypoxic pulmonary hypertension.
结论:内质网应激介导的凋亡与大鼠慢性低氧性肺动脉高压、肺血管改建的病理过程有关。
Conclusion: the endoplasmic reticulum stress-induced apoptosis may be one of the mechanism of hypoxic pulmonary hypertension and pulmonary vascular wall remodeling.
目的应用运动心肺负荷试验早期检出慢性阻塞性肺疾病(COPD)运动性低氧血症及运动性肺动脉高压。
Objective Cardiopulmonary exercise test is used for early detection of exercise induced hypoxia and exercise induced pulmonary arterial hypertension of chronic obstructive pulmonary disease (COPD).
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