每当想到要卖掉自己的房子并搬进养老院，他们就感到极度痛苦。
The idea of having to sell their home and move into a retirement home was an extremely painful experience for them.
我愤怒，愤世嫉俗，情绪感到极度痛苦。
I was angry, cynical, and in a great deal of emotional pain.
他不能实现他的坚定的决心然而感到极度痛苦。
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