前言： 目的：对红细胞生成素胶原蛋白双层微条的体外释放特性进行研究。

Objective: To investigate in vitro release characteristics of collagen double layer minipellet of erythropoietin(EPO).

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结果：单层微条和双层微条中的红细胞生成素分别在第4天和第7天完全释放。

Results: The cumulative release of EPO from single layer minipellet and double layer minipellet reached 100% within 4 days and 7 days, respectively.

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方法：以胶原蛋白为包裹材料，以硫酸软骨素钠为释放调节剂，采用凝胶加压成型的方法制备双层微条；

METHODS:The bilayer minipellet was prepared and shaped by pressurizing gel with the collagen protein as coating material and the sodium chondroitin sulfate as releasing moderator;

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