目的：观察雌激素对骨折愈合过程超微结构变化和骨生长因子骨形态发生蛋白4基因表达及定位分布的影响。

OBJECTIVE to probe into the effect of estrogen on bone microstructure and bone morphogenetic protein-4 mRNA expression and location during fracture healing.

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比较骨形态发生蛋白2 (BMP - 2)基因治疗与生长因子缓释方法修复节段性骨缺损效果。

To compare the effects between gene therapy and gradual release carrier for bone morphogenetic protein-2 (BMP-2) in repairing bone defects.

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两组在骨折后3周和6周的骨形态发生蛋白2及血管内皮生长因子差异无显著性意义（P > 0.05）。

There was no significant difference of BMP-2 and VEGF between experimental group and control group at 3 weeks and 6 weeks after fracture (P > 0.05).

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