细胞到达靶器官、识别移植的异体抗原,启动一系列变化。
The T cell arrives at the target organ, the recognition transplant foreign body antigen, starts a series of changes.
Christopher Garcia领衔的科研小组揭示了T细胞表面受体结构为何能双重识别,该现象也称为同种异体反应性。
Christopher Garcia have established how the structure of receptors on the surface of t cells enables this dual recognition, a phenomenon known as alloreactivity.
Garcia说,这些结构,与我们在其他实验中做的同样好,表现出T细胞受体对异体和自体MHC -蛋白复合物使用完全不同识别机制。
"These structures, as well as other experiments we did, showed that the T-cell receptor USES a completely different recognition mechanism for the foreign and self MHC-protein complex," said Garcia.
应用推荐