伤后脑组织与外界相通的颅脑损伤称为开放性脑损伤。开放性脑损伤分火器伤与非火器伤两类。病理改变大致分为急性期，炎症反应期和并发症期三个时期。
方法对200例开放性颅脑损伤患者的急救与护理措施及治疗结果进行回顾性分析。
Methods the first AIDS, nursing and therapeutic effect of 200 cases of patients with open craniocerebral injury were retrospectively analyzed.
目的探讨开放性颅脑损伤早期清创与预后的关系。
Objective To study the relation between early stage debridement and prognosis after the open head injury.
结论通过民用射钉枪射击致伤，并结合低压氧舱持续减压，可以成功建立模拟高原条件下大鼠低速低能投射物所致的开放性颅脑损伤模型；
Conclusion Combined with using nailer gun shoot and a hypobaric oxygen chamber, the open craniocerebral injury models at simulated high altitude in rats can be established successfully.
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