在染色体平衡易位畸变中,一般都没有遗传物质的丢失,所以个体的表型正常,为平衡易位携带者。平衡易位携带者可能给后代带来患染色体病的高度风险
一位46,xy, t(11; 18)平衡易位携带者的联会复合体分析。
Analysis of Synaptonemal Complex from a Carrier with 46, XY, t (11; 18) Balanced Translocation.
通过遗传咨询门诊,对反复性流产患者夫妇双方或一方进行了染色体核型分析,共71例,检出平衡易位携带者3例。
The karyotypes cf 71 cases of recurrent abortion, or their couples were examined in genetic definition clinic, 3 cases of anomalous karyotype were observed.
染色体平衡易位携带者由于自身染色体是平衡的因此没有异常表型,但将导致不育、流产、死胎、畸胎、胎儿宫内和出生后生长缺陷。
Although the carriers of chromosomal balanced translocation have normal phenotypes they would lead to infertility, abortion of fetus, malformation of fetus and congenital defects after born.
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