多见于胆道阻塞、肝细胞损害或溶血性疾病，由于血液中胆红素升高，致使皮肤黏膜变黄，早期或轻微时见于巩膜，较明显时才见于皮肤。黄疸是指高胆红素血症，临床表现即血中胆红素增高而使巩膜、皮肤、粘膜以及其他组织和体液出现黄染。当血清胆红素浓度为17.1～34.2umol/L(1～2mg/d1)时，而肉眼看不出黄疸者称隐性黄疸。如血清胆红素浓度高于34.2umol/L(2mg/d1)时则为显性黄疸。
服用过量可出现恶心呕吐、腹痛腹泻、疲乏无力、巩膜黄染、神志不清、心动过缓、休克等。
Over dosage can cause nausea, vomiting, abdomen pain with diarrhea, lack of energy, sclera icteric, lack of consciousness, slow heart rate, and shock.
结果9例患者中，4例完全无临床症状，2例有轻度贫血、脾肿大，3例有轻度至中度巩膜黄染。
Results Out of the 9 patients, 4 had no clinical symptoms, 2 showed mild anemia and splenomegaly, 3 were jaundice.
美国食品和药物管理局称，此药上报的最常见的副作用是使用者出现皮肤和巩膜黄染，体虚和腹痛的症状。
The FDA said the most commonly reported adverse reactions included the yellowing of skin or whites of the eyes, weakness and stomach pain.
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