目的研究手性对映体d -柠檬烯和L -柠檬烯对盐酸川芎嗪透皮吸收的影响及其作用机制。
Aim To investigate the effects and permeation mechanism of D-limonene and L-limonene on transdermal delivery of ligustrazine hydrochloride (LH).
目的研究盐酸川芎嗪(TMPH)经大鼠鼻腔给药后的脑内药动学特性。
OBJECTIVE To investigate the brain pharmacokinetics of tetramethylpyrazine hydrochloride (TMPH) after intranasal administration in rats.
方法：采用盐酸川芎嗪进行鼻腔灌流实验。
Methods: The nasal circulatory perfusion test of TMP HCl was performed in rats.
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