尼索地平,药品名为二氢吡啶类钙拮抗剂。对平滑肌、心肌的钙通道有特异阻断作用,可使周围血管扩张、阻力下降,从而使血压下降。还可使冠脉血流量增加,改善心血流,其作用比硝苯啶强而持久,且几乎无负性肌力作用。
尼索地平(Nisoldipine):是一个具有极小电生理和负性肌力效应的强有力的动脉血管扩张剂.对劳力型心绞痛和原发性高血压有一定的疗效,剂量间隔还未确定.
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尼索地平片 Nisoldipine Tablets ; Nisoldipine
尼索地平胶囊 Nisoldipine Capsules
尼索地平杂质 Nisoldipine Related Compound ; Nisoldipine Impurity
间尼索地平 m-Nisoldipine
尼索地平胶丸 Nisoldipine Soft Capsules
尼索地平缓释胶囊 Nisoldipine Sustained Release Capsules
尼索地平软胶囊 Nisoldipine Soft Capsules
间-尼索地平 m-Nisoldipine
尼索地平缓释片 Nisoldipine Sustained-Release Tablets
结果证明,采用固体分散技术能提高尼索地平的体外溶出度。
It is indicated that the solubility of Nisoldipine capsule is improved by the utilization of solid dispersion technology.
目的:建立测定人血浆中尼索地平的毛细管气相色谱电子捕获检测法。
Objective: To establish a capillary GC-ECD method for determining nisoldipine in human plasma.
采用固体分散技术研究和制备了尼索地平胶囊,对其进行了溶出度测定。
The solid dispersion technology was employed in research and development of Nisoldipine capsule. Further more, the dissolution rate was detected upon the capsule.
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