目的评价5%咪喹莫特乳膏治疗尖锐湿疣的疗效和安全性，并与2.5%5-氟脲嘧啶乳膏进行对照。
Objective To observe the clinical efficacy and safety of 5% imiquimod cream in topical treatment of condyloma acuminatum and to compare it with 2.5% fluorouracil(5-FU) cream.
方法采用端粒重复序列扩增文件-酶标法（TRAP-ELISA）测定尖锐湿疣皮损中端粒酶的活性，并与正常皮肤和恶性肿瘤对照比较。
Methods The telomerase activity was detected by TRAP( telomeric repeat amplification protocol) -ELISA which based upon PCR amplification of the initial telomerase product and detected by ELISA.
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