目的构建丙肝病毒核心基因克隆载体pGEM-HCV/core,为进一步研究外部引导序列(external guide sequence,EGS)引导核糖核酸酶P在RNA水平阻断丙肝 ..
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由于核糖核酸酶P识别的是底物的二级结构,因此对于任何序列已知的靶基因mRNA,理论上均可设计一段相应的引导序列(guide sequence,GS)与之结合,并使之形成类似于ptRNA分子的结构,进而被核糖核酸酶P识别并切割,以使该靶基因的表达沉默...
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前导序列 [生化] leader sequence ; targeting sequencing ; leading sequence
指导序列 guide sequence ; internal guide sequence ; IGS
外部指导序列 external guide sequence
外部引导序列 external guide sequence ; EGS
诱导序列 [数] induced sequence
剪接前导序列 spliced leader ; spliced leader sequence
剪接前导序列RNA spliced leader RNA
内部引导序列 interal guide sequence
蛋白质前导序列 Leader sequence of a protein
这种估计方法不需要利用任何训练序列或导频信号，进一步提高了系统频带利用率，降低了计算复杂度。
This estimation algorithm doesn't need any training sequences or pilot signal, therefore improves band efficiency and lower computational complexity.
在初始阶段， 通过设计导频序列，以实现帧级的捕获和脉冲级跟踪；
In the initiation phase, a pilot symbol sequence designed is capitalized to assure frame-level acquisition and pulse-level tracking.
本论文主要针对这个关键技术及相关的最优导频序列设计问题进行了研究。
This thesis focuses on this topic and the corresponding design issue of the optimal pilot sequence.
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