定量药理学是一门交叉学科，涉及到药物动力学模型、药效动力学模型、药效动力学-生物标志物-临床疗效衔接模型，以及统计学、随机模拟和电脑编程等众多学科。
本文主要从新药研发和临床治疗药物监测这两个方面综述了定量药理学国内外研究进展。
This paper reviewed the advances of pharmacometrics employed in new drug research and development and therapeutic drug monitoring both at home and abroad.
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
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