女性2例为完全应答，1例为部分应答。
Female (2cases) was complete response, and 1 cases was part response.
完全应答组IL-4水平在治疗后逐渐下降，部分应答组变化不大；
The level of IL-4 of complete responding group after treatment decreased while the partial responding group didn't.
结论对拉米夫定治疗6个月以上而没有达到病毒学完全应答的患者进行YMDD变异检测，有助于及时调整治疗方案。
Conclusion it would be helpful to adjust the therapeutic regimen by testing YMDD mutations in patients who receive lamivudine therapy more than 6 months without complete virologic response.
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